Spirotetramat, a tetramic acid derivative (ketoenole), is a new insecticide that inhibits lipogenesis in treated insects, resulting in decreased lipid contents, growth inhibition of younger insects, and reduced ability of adult insects to reproduce. Although the intrinsic hazard potential to bees based on the acute oral and contact studies with honey bees appears to be low, brood feeding tests with bees and acute toxicity contact studies with other non-target insects (e.g. parasitoid wasps and predatory mites) conducted at less than the maximum application rate suggest there is potential for mortality in adults and pupae, massive perturbation of brood development, and early brood termination as a result of spirotetramat use.
Source: US Environmental Protection Agency (EPA), Pesticide Fact Sheet, Spirotetramat, June 2008
http://www.epa.gov/opprd001/factsheets/spirotetramat.pdf
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